ELK Biotechnology

SKU:ES10427

UIMC1 rabbit pAb

UIMC1 rabbit pAb

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Size
Applications: WB;ELISA
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 79kD
Human_gene_id: 51720
Human_swiss_prot_no: Q96RL1
Subcellular_location: Nucleus . Localizes at sites of DNA damage at double-strand breaks (DSBs).
Background: ubiquitin interaction motif containing 1(UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
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