TM1L1 rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 52kD
Human_gene_id: 10040
Human_swiss_prot_no: O75674
Subcellular_location: Golgi apparatus, Golgi stack. Endosome membrane . Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . A small proportion is membrane-associated. .
Background: function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,