SYT7 rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 44kD
Human_gene_id: 9066
Human_swiss_prot_no: O43581
Subcellular_location: Cell membrane ; Single-pass membrane protein . Cell junction, synapse, presynaptic cell membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Lysosome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, phagosome membrane ; Single-pass membrane protein . Peroxisome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localization to lysosomes is dependent on N-terminal palmitoylation and interaction with CD63. .
Background: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],