Cleaved-Cathepsin L2 (L114) rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Monkey
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CATL2. AA range:95-144
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 37kD
Human_gene_id: 1515
Human_swiss_prot_no: O60911
Subcellular_location: Lysosome .
Other_name: CTSL2; CATL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V
Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011],