NAC3 rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 530-610
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 101kD
Human_gene_id: 6547
Human_swiss_prot_no: P57103
Subcellular_location: Cell membrane ; Multi-pass membrane protein . Perikaryon . Cell projection, dendrite . Cell projection, dendritic spine . Cell membrane, sarcolemma . Cytoplasm, sarcoplasm . Cell junction . Mitochondrion outer membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Detected at neuromuscular junctions. .
Background: This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013],