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ELK Biotechnology

SKU:ES10146

RELN rabbit pAb

RELN rabbit pAb

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Size
Applications: IHC;IF
Reactivity: Human;Rat
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human protein . at AA range: 270-350
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 380kD
Human_gene_id: 5649
Human_swiss_prot_no: P78509
Subcellular_location: Secreted, extracellular space, extracellular matrix .
Background: This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
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