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ELK Biotechnology

SKU:ES10054

BD1L1 rabbit pAb

BD1L1 rabbit pAb

Regular price $250.00 USD
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Size
Applications: IHC;IF
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human protein . at AA range: 1280-1360
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 335kD
Human_gene_id: 259282
Human_swiss_prot_no: Q8NFC6
Subcellular_location: Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. .
Background: Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.
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