Eps15(Phospho Tyr849) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Eps15 (phospho Tyr849)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

98656

synonyms

Epidermal growth factor receptor substrate 15; EPS15; AF1P; Epidermal growth factor receptor substrate 15; Protein Eps15; Protein AF-1p