ENY2 Antibody

Size

100ug

Clone Number

Aliases

1810057B09Rik antibody; 6720481I12 antibody; DC6 antibody; e(y)2 antibody; Enhancer of yellow 2 transcription factor homolog antibody; eny2 antibody; ENY2_HUMAN antibody; Ey2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NPA8

Immunogen

Recombinant Human Transcription and mRNA export factor ENY2 protein (1-101AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ENY2

Research Areas

Epigenetics and Nuclear Signaling; Cell biology; Signal transduction