ENPP1 Antibody

Size

100ug

Clone Number

Aliases

Alkaline phosphodiesterase 1 antibody; ARHR2 antibody; COLED antibody; E-NPP 1 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 antibody; ENPP1 antibody; ENPP1_HUMAN antibody; Ly 41 antigen antibody; M6S1 antibody; Membrane component chromosome 6 surface marker 1 antibody; NPP1 antibody; NPPase antibody; NPPS antibody; Nucleotide pyrophosphatase antibody; PC 1 antibody; PC-1 antibody; PCA1 antibody; PDNP1 antibody; Phosphodiesterase I/nucleotide pyrophosphatase 1 antibody; Plasma cell membrane glycoprotein 1 antibody; Plasma-cell membrane glycoprotein PC-1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P22413

Immunogen

Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 protein (1-75AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5\' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3\',5\'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ENPP1

Research Areas

Cell biology; Metabolism; Signal transduction