ENG Monoclonal Antibody

Size

100ul

Clone Number

Aliases

Endoglin (CD antigen CD105), ENG, END

Immunogen Species

Homo sapiens (Human)

UniProt ID

P17813

Immunogen

Synthesized peptide derived from human CD105(Endoglin)

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Clonality

Monoclonal

Isotype

IgG2b, Kappa

Purification Method

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugate

Non-conjugated

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ENG

Research Areas

Immunology