ENG Antibody

Size

100ul

Clone Number

Aliases

AI528660 antibody; AI662476 antibody; CD 105 antibody; CD105 antibody; CD105 antigen antibody; EGLN_HUMAN antibody; END antibody; Endoglin antibody; Eng antibody; FLJ41744 antibody; HHT1 antibody; ORW antibody; ORW1 antibody; Osler Rendu Weber syndrome 1 antibody; RP11 228B15.2 antibody; S endoglin antibody; S-endoglin antibody; SN6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P17813

Immunogen

Recombinant Human Endoglin protein (32-259AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ENG

Research Areas

Cancer; Cardiovascular; Immunology; Stem cells