ENDOG Antibody

Size

100ug

Clone Number

Aliases

ENDOG antibody; Endonuclease G antibody; mitochondrial antibody; Endo G antibody; EC 3.1.30.- antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q14249

Immunogen

Recombinant Human Endonuclease G, mitochondrial protein (49-297AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ENDOG

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism