EMR3 Polyclonal Antibody

Ab type

Primary antibody

Background

ADGRE3 (adhesion G protein-coupled receptor E3) encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. ADGRE3 is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human EMR3. AA range:603-652

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

72593

synonyms

EMR3; EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3