Eme1 Polyclonal Antibody

Ab type

Primary antibody

Background

EME1 encodes essential meiotic structure-specific endonuclease 1 that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Eme1 . at AA range: 250-330

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

63252

synonyms

EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4