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ELK Biotechnology

SKU:EM1374

ATG5 (3C7) Mouse mAb

ATG5 (3C7) Mouse mAb

Regular price $250.00 USD
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Size
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Source: Mouse
Dilution: WB  1:5,000-10,000 IHC 1:100-200
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 55kDa
Human_gene_id: 9494
Human_swiss_prot_no: Q9H1Y0
Subcellular_location: Cytoplasm, Membrane
Other_name: APG5, APG5L, ASP, Autophagy protein 5 antibody
Background: Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
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