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ELK Biotechnology

SKU:EM1372

Collagen II (8F6) Mouse mAb

Collagen II (8F6) Mouse mAb

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Size
Applications: IHC
Reactivity: Human, Mouse, Rat
Source: Mouse
Dilution: IHC 1:100-200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 142kDa
Human_gene_id: 1280
Human_swiss_prot_no: P02458
Subcellular_location: Secreted,extracellular space,extracellular matrix
Other_name: Alpha 1 type II collagen , AOM, Col2a1 antibody
Background: Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.
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