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ELK Biotechnology

SKU:EM1342

Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb

Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb

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Size
Applications: IHC
Reactivity: Human, Mouse, Rat
Source: Mouse
Dilution: IHC 1:100-200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 44,42kDa
Human_gene_id: 5594/5595
Human_swiss_prot_no: P27361/P28482
Subcellular_location: Nucleus
Other_name: MAPK, Mitogen-activated protein Kinase, PRKM2,MK01
Background: Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.
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