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ELK Biotechnology
SKU:EM1328
MLKL (8H7) Mouse mAb
MLKL (8H7) Mouse mAb
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$250.00 USD
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Applications: IHC
Reactivity: Human
Source: Mouse
Dilution: IHC 1:100-200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 54kDa
Human_gene_id: 197259
Human_swiss_prot_no: Q8NB16
Subcellular_location: Cell membrane, Cytoplasm, Membrane
Other_name: Mixed lineage kinase domain like protein, FLJ34389
Background: Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
Reactivity: Human
Source: Mouse
Dilution: IHC 1:100-200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 54kDa
Human_gene_id: 197259
Human_swiss_prot_no: Q8NB16
Subcellular_location: Cell membrane, Cytoplasm, Membrane
Other_name: Mixed lineage kinase domain like protein, FLJ34389
Background: Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
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