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ELK Biotechnology

SKU:EM1079

ErbB-2/HER-2 Mouse mAb

ErbB-2/HER-2 Mouse mAb

Regular price $250.00 USD
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Size
Applications: WB, IHC
Reactivity: Human
Source: Mouse
Dilution: WB 1:1,000  IHC 1:200-500
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 138kDa
Human_gene_id: 2064
Human_swiss_prot_no: P04626
Subcellular_location: Cytoplasm. Nucleus and Cell membrane
Other_name: CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1
Background: ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.
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