Skip to product information
1 of 1

ELK Biotechnology

SKU:EM1076

CA IX/Carbonic Anhydrase IX Mouse mAb

CA IX/Carbonic Anhydrase IX Mouse mAb

Regular price $250.00 USD
Regular price Sale price $250.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
Applications: WB, IHC, IP
Reactivity: Human
Source: Mouse
Dilution: WB 1:3,000 IP 1:200  IHC 1:100-200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 35-38kDa
Human_gene_id: 768
Human_swiss_prot_no: Q16790
Subcellular_location: Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane.
Other_name: CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC associated antigen G250
Background: The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.
View full details