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ELK Biotechnology
SKU:EM1066
NSE Mouse mAb
NSE Mouse mAb
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$250.00 USD
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Applications: WB, IHC
Reactivity: Human, Rat, Mouse
Source: Mouse
Dilution: WB 1:2,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 47kDa
Human_gene_id: 2026
Human_swiss_prot_no: P09104
Subcellular_location: Cytoplasm. Cell membrane.
Other_name: ENO2, Enolase 2, enolase 2 (gamma, neuronal), Gamma enolase, Neural enolase, Neuron specific enolase
Background: Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.
Reactivity: Human, Rat, Mouse
Source: Mouse
Dilution: WB 1:2,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 47kDa
Human_gene_id: 2026
Human_swiss_prot_no: P09104
Subcellular_location: Cytoplasm. Cell membrane.
Other_name: ENO2, Enolase 2, enolase 2 (gamma, neuronal), Gamma enolase, Neural enolase, Neuron specific enolase
Background: Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.
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