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ELK Biotechnology
SKU:EM1059
GFAP Mouse mAb
GFAP Mouse mAb
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$250.00 USD
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$250.00 USD
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Applications: WB, IHC
Reactivity: Rat, Mouse
Source: Mouse
Dilution: WB 1:2,000-5,000 IHC 1:200-500
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 45kDa
Human_gene_id: 2670
Human_swiss_prot_no: P14136
Subcellular_location: Cytoplasm. Associated with intermediate filaments
Other_name: Glial Fibrillary Acidic Protein ;Intermediate Filament Protein
Background: GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
Reactivity: Rat, Mouse
Source: Mouse
Dilution: WB 1:2,000-5,000 IHC 1:200-500
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 45kDa
Human_gene_id: 2670
Human_swiss_prot_no: P14136
Subcellular_location: Cytoplasm. Associated with intermediate filaments
Other_name: Glial Fibrillary Acidic Protein ;Intermediate Filament Protein
Background: GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
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