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ELK Biotechnology
SKU:EM1057
CDX2 Mouse mAb
CDX2 Mouse mAb
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$250.00 USD
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$250.00 USD
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Applications: WB, IHC
Reactivity: Human, Rat, Mouse
Source: Mouse
Dilution: WB 1:1,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 42kDa
Human_gene_id: 1045
Human_swiss_prot_no: Q99626
Subcellular_location: Nucleus
Other_name: Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2
Background: CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.
Reactivity: Human, Rat, Mouse
Source: Mouse
Dilution: WB 1:1,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 42kDa
Human_gene_id: 1045
Human_swiss_prot_no: Q99626
Subcellular_location: Nucleus
Other_name: Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2
Background: CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.
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