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ELK Biotechnology

SKU:EM1035

Lamin B1 Mouse mAb

Lamin B1 Mouse mAb

Regular price $250.00 USD
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Size
Applications: WB, IP
Reactivity: Human, Rat, Mouse
Source: Mouse
Dilution: WB 1:2,000-5,000 IP 1:200
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 68kDa
Human_gene_id: 4001
Human_swiss_prot_no: P20700
Subcellular_location: Mitochondrion inner membrane
Other_name: ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218
Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
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