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ABCbiolab

SKU:ABCCS43436

ELOVL2 Antibody

ELOVL2 Antibody

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Size

100ug

Clone Number

Aliases

3 keto acyl CoA synthase ELOVL2 antibody; 3-keto acyl-CoA synthase Elovl2 antibody; Elongation of very long chain fatty acids (FEN1/Elo2; SUR4/Elo3; yeast) like 2 antibody; Elongation of very long chain fatty acids protein 2 antibody; ELOV2_HUMAN antibody; ELOVL fatty acid elongase 2 antibody; Elovl2 antibody; FLJ20334 antibody; OTTHUMP00000016029 antibody; SSC2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NXB9

Immunogen

Recombinant Human Elongation of very long chain fatty acids protein 2 protein (91-174AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ELOVL2

Research Areas

Cardiovascular; Metabolism; Signal transduction

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