ELOVL1 Antibody

Size

100ug

Clone Number

Aliases

3 keto acyl CoA synthase ELOVL1 antibody; 3-keto acyl-CoA synthase ELOVL1 antibody; CGI 88 antibody; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1 antibody; Elongation of very long chain fatty acids like 1 antibody; Elongation of very long chain fatty acids protein 1 antibody; ELOV1_HUMAN antibody; ELOVL 1 antibody; ELOVL FA elongase 1 antibody; ELOVL fatty acid elongase 1 antibody; ELOVL1 antibody; Ssc1 antibody; Ssc1; mouse; homolog of antibody; very long chain 3 oxoacyl CoA synthase 1 antibody; Very-long-chain 3-oxoacyl-CoA synthase 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BW60

Immunogen

Recombinant Human Elongation of very long chain fatty acids protein 1 protein (82-175AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ELOVL1

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction