EKLF Polyclonal Antibody

Ab type

Primary antibody

Background

KLF1 encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

38221

synonyms

KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF