eIF4B(Phospho Ser422) Polyclonal Antibody

Ab type

Primary antibody

Background

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422. AA range:388-437

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

69224

synonyms

Eukaryotic translation initiation factor 4B; EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B