EIF3M Antibody

Size

100ug

Clone Number

Aliases

B5 antibody; B5 receptor antibody; Dendritic cell protein antibody; eIF3m antibody; EIF3M_HUMAN antibody; Eukaryotic translation initiation factor 3 subunit M antibody; Fetal lung protein B5 antibody; FLJ29030 antibody; GA17 antibody; hfl B5 antibody; hFL-B5 antibody; PCI domain containing 1 (herpesvirus entry mediator) antibody; PCI domain-containing protein 1 antibody; PCID1 antibody; TANGO7 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q7L2H7

Immunogen

Recombinant Human Eukaryotic translation initiation factor 3 subunit M protein (2-374AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

EIF3M

Research Areas

Microbiology