EIF3F Antibody

Size

100ul

Clone Number

Aliases

Deubiquitinating enzyme eIF3f antibody; eIF 3 epsilon antibody; eIF-3-epsilon antibody; eIF3 p47 antibody; eIF3 p47 subunit antibody; eIF3-epsilon antibody; eIF3-p47 antibody; eIF3f antibody; EIF3F_HUMAN antibody; EIF3S5 antibody; EIF3S5; formerly antibody; Eukaryotic translation initiation factor 3 subunit 5 antibody; Eukaryotic translation initiation factor 3 subunit 5; formerly antibody; Eukaryotic translation initiation factor 3 subunit F antibody; eukaryotic translation initiation factor 3; subunit 5 (epsilon; 47kD) antibody; eukaryotic translation initiation factor 3; subunit 5 epsilon; 47kDa antibody; eukaryotic translation initiation factor 3; subunit F antibody; translation initiation factor 3 47 kda subunit antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O00303

Immunogen

Recombinant Human Eukaryotic translation initiation factor 3 subunit F protein (88-357AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

EIF3F

Research Areas

Epigenetics and Nuclear Signaling