EHF Antibody

Size

100ul

Clone Number

Aliases

EHF antibody; EHF_HUMAN antibody; Epithelium-specific Ets transcription factor 3 antibody; ESE-3 antibody; ESE3 antibody; ESE3 transcription factor antibody; ESE3B antibody; ESEJ antibody; Ets domain transcription factor antibody; ETS domain-containing transcription factor antibody; ETS homologous factor antibody; hEHF antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NZC4

Immunogen

Recombinant Human ETS homologous factor protein (1-210AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter. May contribute to development and carcinogenesis by acting as a tumor suppressor gene or anti-oncogene.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

EHF

Research Areas

Epigenetics and Nuclear Signaling