EFNB3 Antibody

Size

100ul

Clone Number

Aliases

EFL 6 antibody; EFL6 antibody; EFNB 3 antibody; Efnb3 antibody; EFNB3_HUMAN antibody; EPH related receptor transmembrane ligand ELK L3 antibody; EPH related receptor transmembrane ligand ELKL3 antibody; EPH related receptor tyrosine kinase ligand 8 antibody; EPH-related receptor transmembrane ligand ELK-L3 antibody; EPH-related receptor tyrosine kinase ligand 8 antibody; Ephrin B3 antibody; Ephrin-B3 antibody; EphrinB3 antibody; EPLG 8 antibody; EPLG8 antibody; LERK 8 antibody; LERK-8 antibody; LERK8 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15768

Immunogen

Recombinant Human Ephrin-B3 protein (28-226AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

EFNB3

Research Areas

Neuroscience; Cardiovascular