EF-1  Alpha1/2 (Acetyl Lys41) Polyclonal Antibody

Ab type

Primary antibody

Background

EEF1A1 encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. eukaryotic translation elongation factor 1 alpha 1 is identified as an autoantigen in 66% of patients with Felty syndrome. EEF1A1 has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized Acetyl-peptide derived from human EEF1A around the Acetylation site of Lys41. AA range:1-50

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

50141/50470/50185

synonyms

EEF1A1; EEF1A; EF1A; LENG7; Elongation factor 1-alpha 1; EF-1-alpha-1; Elongation factor Tu; EF-Tu; Eukaryotic elongation factor 1 A-1; eEF1A-1; Leukocyte receptor cluster member 7; EEF1A2; EEF1AL; ST