EDA Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for EDA.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human EDA. AA range:120-170

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

43010

synonyms

EDA; ED1; EDA2; Ectodysplasin-A; Ectodermal dysplasia protein; EDA protein