ECM1 Polyclonal Antibody

Ab type

Primary antibody

Background

ECM1 encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the N-terminal region of human ECM1.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

60674

synonyms

ECM1; Extracellular matrix protein 1; Secretory component p85