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ELK Biotechnology

SKU:EA304

KChIP1 Rabbit pAb

KChIP1 Rabbit pAb

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Size
Applications: IHC
Reactivity: Human, Mouse
Source: Rabbit
Dilution: IHC 1:100-200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 30kDa
Human_gene_id: 30820
Human_swiss_prot_no: Q9NZI2
Subcellular_location: Cell membrane, Cell projection, Cytoplasm, Membrane
Other_name: KCNIP1,MGC9,MGC95,A type potassium channel modulatory protein 1
Background: Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death.
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