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ELK Biotechnology

SKU:EA214

Calnexin Rabbit pAb

Calnexin Rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB, IHC
Reactivity: Human, Rat, Mouse
Source: Rabbit
Dilution: WB 1:1,000-2,000   IHC 1:200-500
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 75,80,90kDa
Human_gene_id: 821
Human_swiss_prot_no: P27824
Subcellular_location: Endoplasmic reticulum membrane,Melanosome.
Other_name: CANX antibody, CNX antibody, FLJ26570 antibody, IP90 antibody, P90 antibody
Background: Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail.
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