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ELK Biotechnology

SKU:EA213

IκB α Rabbit pAb

IκB α Rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB, IHC
Reactivity: Human, Rat
Source: Rabbit
Dilution: WB 1:2,000-5,000   IHC  1:200-500
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 40kDa
Human_gene_id: 4792
Human_swiss_prot_no: P25963
Subcellular_location: Cytoplasm,Nucleus
Other_name: I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody
Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.
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