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ELK Biotechnology
SKU:EA147
β-Catenin Rabbit pAb
β-Catenin Rabbit pAb
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$250.00 USD
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Applications: WB, IHC
Reactivity: Mouse, Rat
Source: Rabbit
Dilution: WB 1:1,000 IHC 1:500-1,000
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 92kDa
Human_gene_id: 1499
Human_swiss_prot_no: P35222
Subcellular_location: Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus, Synapse
Other_name: beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082
Background: The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
Reactivity: Mouse, Rat
Source: Rabbit
Dilution: WB 1:1,000 IHC 1:500-1,000
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 92kDa
Human_gene_id: 1499
Human_swiss_prot_no: P35222
Subcellular_location: Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus, Synapse
Other_name: beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082
Background: The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
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