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ELK Biotechnology

SKU:EA056

Cytokeratin 18 Rabbit pAb

Cytokeratin 18 Rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB, IHC
Reactivity: Human, Rat, Mouse
Source: Rabbit
Dilution: WB 1:1,000-2,000  IHC 1:500-1,000
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 46kDa
Human_gene_id: 3875
Human_swiss_prot_no: P05783
Subcellular_location: Cytoplasm, Intermediate filament, Keratin, Nucleus
Other_name: Cell proliferation inducing gene 46 protein, CK 18, CYK 18, K 18, Keratin 18, Ketatin D, KRT18
Background: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
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