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ELK Biotechnology

SKU:EA041

Lamin B1 Rabbit pAb

Lamin B1 Rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB, IHC
Reactivity: Human, Rat, Mouse
Source: Rabbit
Dilution: WB 1:1,000-3,000  IHC: 1:500-1,000
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 68,45kDa
Human_gene_id: 4001
Human_swiss_prot_no: P20700
Subcellular_location: Mitochondrion inner membrane
Other_name: ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218
Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
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