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ELK Biotechnology

SKU:EA022

FH/Fumarase Rabbit pAb

FH/Fumarase Rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB, IF
Reactivity: Human, Rat, Mouse
Source: Rabbit
Dilution: WB 1:1,000
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 50kDa
Human_gene_id: 2271
Human_swiss_prot_no: P07954
Other_name: Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
Background: Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate in the mitochondria. Fumarase deficiency is caused by a mutation in the fumarase gene in humans. Fumarase deficiency is one of the few known deficiencies of the Krebs cycle or tricarboxylic acid cycle, the main enzymatic pathway of cellular aerobic respiration.
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