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ELK Biotechnology

SKU:EA020

MeCP2 Rabbit pAb

MeCP2 Rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB
Reactivity: Human
Source: Rabbit
Dilution: WB 1:2,000
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed_band(KD): 53kDa
Human_gene_id: 4204
Human_swiss_prot_no: P51608
Subcellular_location: Nucleus
Other_name: Methyl CpG Binding Protein 2 ;RTS; AUTSX3; MRX16; MRX79; PPMX; RTT; Rett Syndrome; Mental Retardation,X-linked 16
Background: Methyl-CpG-binding protein 2(MeCP2), whose exact function is unclear. It appears to help regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein usually regulates genes involved in brain function, even though this protein is found throughout the body.Within the brain, the MeCP2 protein is important for the function of nerve cells (neurons) and is present in high levels in mature neurons. This protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. Many of the genes that are known to be regulated by the MeCP2 protein play a role in normal brain function, particularly the maintenance of synapses.
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