E2F4 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

E2F 4 antibody; E2F transcription factor 4 antibody; E2F transcription factor 4 p107/p130 binding antibody; E2F-4 antibody; E2F4 antibody; E2F4_HUMAN antibody; p107/p130 binding protein antibody; Transcription factor E2F 4 antibody; Transcription factor E2F4 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q16254

Immunogen

Recombinant Human Transcription factor E2F4 protein (160-299AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5\'-TTTC[CG]CGC-3\' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

E2F4

Research Areas

Epigenetics and Nuclear Signaling; Stem cells