E-Ras Polyclonal Antibody

Ab type

Primary antibody

Background

ERAS encodes a constitutively active member of the small GTPase Ras protein family. The ES cell expressed Ras activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. ERAS may be involved in cancer and chemotherapy resistance.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ERAS. AA range:184-233

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

25287

synonyms

ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras