DYNC1LI1 Antibody

Size

100ul

Clone Number

Aliases

Cytoplasmic dynein 1 light intermediate chain 1 antibody; cytosolic antibody; DC1L1_HUMAN antibody; DLC-A antibody; DNCLI1 antibody; dync1li1 antibody; Dynein cytoplasmic 1 light intermediate chain 1 antibody; Dynein cytoplasmic light intermediate polypeptide 1 antibody; Dynein light chain A antibody; Dynein light intermediate chain 1 antibody; Dynein light intermediate chain 1 cytosolic antibody; FLJ10219 antibody; LIC1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y6G9

Immunogen

Recombinant Human Cytoplasmic dynein 1 light intermediate chain 1 protein (167-233AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DYNC1LI1

Research Areas

Others