DYNC1I1 Antibody

Size

100ul

Clone Number

Aliases

Cytoplasmic dynein 1 intermediate chain 1 antibody; Cytoplasmic dynein intermediate chain 1 antibody; cytosolic antibody; DC1I1_HUMAN antibody; DH IC 1 antibody; DH IC-1 antibody; DH IC1 antibody; DNCI1 antibody; DNCIC1 antibody; Dync1i1 antibody; Dynein cytoplasmic 1 intermediate chain 1 antibody; Dynein intermediate chain 1 antibody; Dynein intermediate chain 1; cytosolic antibody; Dynein; cytoplasmic; intermediate polypeptide 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O14576

Immunogen

Recombinant Human Cytoplasmic dynein 1 intermediate chain 1 protein (1-220AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DYNC1I1

Research Areas

Signal transduction