Dynamin I Polyclonal Antibody

Ab type

Primary antibody

Background

DNM1 encodes a member of the dynamin subfamily of GTP-binding proteins. Dynamin 1 possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Dynamin-1. AA range:740-789

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

97407

synonyms

DNM1; DNM; Dynamin-1