DXO Antibody

Size

100ug

Clone Number

Aliases

Dom 3 homolog Z antibody; DOM 3Z antibody; Dom-3 homolog Z antibody; DOM3 C. elegans homolog of Z antibody; Dom3 homolog Z antibody; DOM3L antibody; Dom3z antibody; DOM3Z_HUMAN antibody; NG6 antibody; Protein Dom3Z antibody; RAI1 antibody; RAT1-INTERACTING PROTEIN 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O77932

Immunogen

Recombinant Human Decapping and exoribonuclease protein (69-266AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Ribonuclease that specifically degrades pre-mRNAs with a defective 5\' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5\'-3\' exonuclease activities. Has decapping activity toward incomplete 5\' end cap mRNAs such as unmethylated 5\' end-capped RNA to release GpppN and 5\' end monophosphate RNA. The 5\' end monophosphate RNA is then degraded by the 5\'-3\' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5\'-pyrophosphohydrolase activity by hydrolyzing the 5\' end triphosphate to release pyrophosphates (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DXO

Research Areas

Others